The only way to see Pittsburgh is from the top of this lookout point, just like the ancient members of the native peoples did.

One of the steepest streets in the United States makes an intriguing challenge for cyclists.

Found art has transformed this Pittsburgh neighborhood into a psychedelic dream.

St. Francesca Romana, patron saint of drivers, resides in the church she founded.

This historic recreationist school churns out warriors that may very well have had a fighting chance in Rome's pits of the day.

A Milanese café entirely designed by the American director Wes Anderson.

The martyr's wax-enhanced skeletal remains lie preserved in a glass case in the Santa Maria della Vittoria in Rome.

This ritzy Italian market is built around a statue of an unforgiven heretic who was burned for his belief in an endless universe.

Over 50 exquisite hand-painted Renaissance maps decorate a Medici storage room.

Jesus' footprints and the first catacombs in the world.

2300-year-old Roman road connecting the empire.

The oldest operating pharmacy in the world features 800-year-old recipes.

A submerged archeological park still holds the wonders of a Roman Sodom.

Hundreds of lucky felines haunt the ruins where Caesar was murdered.

Ample proof that watery ends make for well-preserved, millenia-old mummies.

A Black Forest cuckoo clock theme park features one timepiece big enough to walk inside.

These blingy, baubled skeletons lie in glass boxes inside a baroque Bavarian church.

A wunderkammer of mysterious objects and stories.

A surreal museum of extraordinary industrial objects.

Small on the outside, big on the inside, this church is an astonishing act of visual deception.

A space dedicated to contemporary art and culture, co-chaired by fashion icon Miuccia Prada.

This curious building hides eclectic details like medieval gargoyles alongside naked angels and Art Nouveau mosaics.

One of the world’s smallest bars, just 13 square feet, is brimming with speakeasy flair.

An ossuary built in 1210 to collect bones from the Ospedale Maggiore of Milan.