The curiosities and wonders of pharmacy in a delightful historic building.

This symbolic piece of New Orleans architecture is also home to a few ghastly stories.

A snapshot of the city's fascinating voodoo culture.

A museum and shop on Bourbon Street located in the French Quarter.

This strange, small castle on the bayou has withstood the test of time and weather.

This distinctive Crescent City tradition dates back to the days of horse-drawn carriages.

The oldest operational cathedral in the U.S. has one shell of a way of projecting speakers' voices.

This cathedral dedicated to Louis IX, sainted King of France, holds many secrets.

Legend says a primate-like cryptid prowls this otherworldy sliver of the Louisiana bayou.

Welcome to old Florida, where a 1940s mermaid show is still enchanting visitors.

In this case, 'zero' marks the spot where the iconic Old Spanish Trail ends.

America's first wax museum opened in 1948.

Built around 1723, this is the oldest surviving home in the U.S.'s oldest colonial city.

A luxurious 1880s hotel with its fair share of Tiffany stained glass, Edison electricity, and of course, ghosts.

St. Augustine's record-setting narrow street was designed to protect against pirates.

An early-19th-century hotel with a past that is steeped in the Civil War.

The first public building in Savannah to offer air conditioning was a luxurious cinema that still operates today.

A historic canal winds through a unique, swampy landscape.

More than a century after her death, Little Gracie Watson remains one of Savannah's most often-visited residents.

An eerie smiling woman looms above the granite tombstones.

One of Savannah's oldest and most haunted cemeteries, featuring graves desecrated by Sherman's Union Army.

A statue honoring 44 continuous years of greeting passing ships.

This kitschy tavern is also home to rare early editions of "Treasure Island."

Local myth claims this is a Sears catalogue home with its windows installed upside-down.